Anti-Cd24 antibody [M1/69] {AF488} (STJA0001986)

SKU:
STJA0001986

Current Stock:
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Signal transducer CD24 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: M1/69
Conjugation: AF488
Isotype: IgG2bk
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Cd24
Gene ID: 12484
Uniprot ID: CD24_MOUSE
Tissue Specificity In lymphoid, myeloid, and erythroid cells.
Post Translational Modifications The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc.
Function May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name Signal Transducer Cd24
Lymphocyte Antigen 52
Ly-52
M1/69-J11d Heat Stable Antigen
Hsa
Nectadrin
R13-Ag
X62 Heat Stable Antigen
Cd Antigen Cd24
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Signal Transducer Cd24 antibody
Anti-Lymphocyte Antigen 52 antibody
Anti-Ly-52 antibody
Anti-M1/69-J11d Heat Stable Antigen antibody
Anti-Hsa antibody
Anti-Nectadrin antibody
Anti-R13-Ag antibody
Anti-X62 Heat Stable Antigen antibody
Anti-Cd Antigen Cd24 antibody
Anti-Cd24 antibody
Anti-Cd24a antibody
Anti-Ly-52 antibody

Information sourced from Uniprot.org

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