Anti-CD23/Fcer2 antibody [B3B4] {PE} (STJA0001982)
SPECIFICATIONS
ClonalityMonoclonal
HostRat
ConjugationPE
IsotypeIgG2ak
General Information
| Short Description | Rat monoclonal anti-Low affinity immunoglobulin epsilon Fc receptor for use in FC in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | B3B4 |
| Isotype | IgG2ak |
| Conjugation | PE |
| Concentration | 0.2 mg/mL |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8ยฐC and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | Fcer2 |
| Gene ID | 14128 |
| Uniprot ID | FCER2_MOUSE |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc ReceptorFc-Epsilon-RiiLymphocyte Ige ReceptorCd Antigen Cd23 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorSecreted |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibodyAnti-Fc-Epsilon-Rii antibodyAnti-Lymphocyte Ige Receptor antibodyAnti-Cd Antigen Cd23 antibodyAnti-Fcer2 antibodyAnti-Fcer2a antibody |
Information sourced from Uniprot.org