Anti-CD215/IL-15R Alpha antibody {ABflo® 488} (STJ11108840)

SKU:
STJ11108840
€154.20 - €433.80
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Applications:IF/ICC/FC
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:ABflo® 488
Purification:Affinity purification
Dilution Range:IF/ICC, 1:50-1:200|FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Formulation:PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3.
Storage Instruction:Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol:Il15ra
Gene ID:16169
Uniprot ID:I15RA_MOUSE
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Widely expressed.
Post Translational Modifications N-glycosylated and O-glycosylated. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. It also binds IL15 and thus interferes with IL15 binding to the membrane receptor.
Function High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner.
Protein Name Interleukin-15 Receptor Subunit Alpha
Il-15 Receptor Subunit Alpha
Il-15r-Alpha
Il-15ra
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha
Sil-15 Receptor Subunit Alpha
Sil-15r-Alpha
Sil-15ra
Database Links Reactome: R-MMU-8983432
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Nucleus Membrane
Cell Surface
Soluble Interleukin-15 Receptor Subunit Alpha: Secreted
Extracellular Space
Alternative Antibody Names Anti-Interleukin-15 Receptor Subunit Alpha antibody
Anti-Il-15 Receptor Subunit Alpha antibody
Anti-Il-15r-Alpha antibody
Anti-Il-15ra antibody
Anti-Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha antibody
Anti-Sil-15 Receptor Subunit Alpha antibody
Anti-Sil-15r-Alpha antibody
Anti-Sil-15ra antibody
Anti-Il15ra antibody

Information sourced from Uniprot.org

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