Anti-CD21 antibody [2G9] (STJ16101703)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenProkaryotic recombinant protein corresponding to the external domain of the human CD21 molecule.
STJ16101703-1
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General Information

Short DescriptionMouse monoclonal anti-CD21 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID2G9
IsotypeIgG2a
ConjugationUnconjugated
Concentration>=326 mg/L
Dilution RangeIHC-P 1:80
FormulationTissue culture supernatant with sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenProkaryotic recombinant protein corresponding to the external domain of the human CD21 molecule.

Additional Info

Background CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.

Information sourced from Uniprot.org

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