Anti-CD21 antibody [2G9] (STJ16101703)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenProkaryotic recombinant protein corresponding to the external domain of the human CD21 molecule.
General Information
| Short Description | Mouse monoclonal anti-CD21 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2G9 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | >=326 mg/L |
| Dilution Range | IHC-P 1:80 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Prokaryotic recombinant protein corresponding to the external domain of the human CD21 molecule. |
Additional Info
| Background | CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas. |
Information sourced from Uniprot.org