![Anti-CD21 antibody [2G9] (STJ16100329)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149046/346662/STJ16100329_1__53662.1681998739.jpg?c=1 "Anti-CD21 antibody [2G9] (STJ16100329)")
![Anti-CD21 antibody [2G9] (STJ16100329)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149046/346662/STJ16100329_1__53662.1681998739.jpg?c=1 "Anti-CD21 antibody [2G9] (STJ16100329)")
Anti-CD21 antibody [2G9] (STJ16100329)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal anti-CD21 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2G9 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1:25-1:100 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
Additional Info
| Background | CD21 (also known as complement receptor 2 (CR2) , C3d receptor, or EBV receptor) is a 140 kDa membrane protein on B-lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. The antigen is absent on T-lymphocytes, monocytes, and granulocytes. MON 3027 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue. This antibody also labels follicular dendritic cell sarcomas. Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in distinguishing among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers.6 Anti-CD21 is also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma. |
Information sourced from Uniprot.org