| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C-type lectin domain family 4 member K (61-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CD207 |
| Gene ID: |
50489 |
| Uniprot ID: |
CLC4K_HUMAN |
| Immunogen Region: |
61-110 aa |
| Specificity: |
CD207 Polyclonal Antibody detects endogenous levels of CD207 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human CD207 at the amino acid range 61-110 |
| Function | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs).is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
| Protein Name | C-Type Lectin Domain Family 4 Member KLangerinCd Antigen Cd207 |
| Database Links | Reactome: R-HSA-1236978 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinFound In Birbeck Granules (Bgs)Which Are Organelles Consisting Of Superimposed And Zippered Membranes |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member K antibodyAnti-Langerin antibodyAnti-Cd Antigen Cd207 antibodyAnti-CD207 antibodyAnti-CLEC4K antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
