Anti-CD207 antibody (61-110 aa) (STJ96640)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD207 at the amino acid range 61-110
General Information
| Short Description | Rabbit polyclonal anti-C-type lectin domain family 4 member K (61-110 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD207 |
| Gene ID | 50489 |
| Uniprot ID | CLC4K_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CD207 at the amino acid range 61-110 |
| Immunogen Region | 61-110 aa |
| Specificity | CD207 Polyclonal Antibody detects endogenous levels of CD207 protein. |
Additional Info
| Function | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs).is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
| Protein Name | C-Type Lectin Domain Family 4 Member KLangerinCd Antigen Cd207 |
| Database Links | Reactome: R-HSA-1236978 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinFound In Birbeck Granules (Bgs)Which Are Organelles Consisting Of Superimposed And Zippered Membranes |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member K antibodyAnti-Langerin antibodyAnti-Cd Antigen Cd207 antibodyAnti-CD207 antibodyAnti-CLEC4K antibody |
Information sourced from Uniprot.org