Anti-CD201/EPCR antibody {ABflo® 647} (STJ11108617)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 647
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD201/EPCR antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 647 |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | PROCR |
| Gene ID | 10544 |
| Uniprot ID | EPCR_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. |
| Post Translational Modifications | N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. |
| Function | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation. |
| Protein Name | Endothelial Protein C ReceptorActivated Protein C ReceptorApc ReceptorEndothelial Cell Protein C ReceptorCd Antigen Cd201 |
| Database Links | Reactome: R-HSA-140875Reactome: R-HSA-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Endothelial Protein C Receptor antibodyAnti-Activated Protein C Receptor antibodyAnti-Apc Receptor antibodyAnti-Endothelial Cell Protein C Receptor antibodyAnti-Cd Antigen Cd201 antibodyAnti-PROCR antibodyAnti-EPCR antibody |
Information sourced from Uniprot.org