Anti-CD20/MS4A1 antibody [2H7] (STJA0002192)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
General Information
| Short Description | Mouse monoclonal anti-B-lymphocyte antigen CD20 for use in Depletion, FC, IHC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | Depletion/FC/IHC/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2H7 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Formulation | 0.2 ยตm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Storage Instruction | This product can be stored at 2-8ยฐC for 12 months. Do not freeze. |
Target Information
| Gene Symbol | MS4A1 |
| Gene ID | 931 |
| Uniprot ID | CD20_HUMAN |
Additional Info
| Tissue Specificity | Expressed on B-cells. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibodyAnti-B-Lymphocyte Surface Antigen B1 antibodyAnti-Bp35 antibodyAnti-Leukocyte Surface Antigen Leu-16 antibodyAnti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibodyAnti-Cd Antigen Cd20 antibodyAnti-MS4A1 antibodyAnti-CD20 antibody |
Information sourced from Uniprot.org