| Host: |
Mouse |
| Applications: |
FC/FUNC/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD20 is suitable for use in Flow Cytometry, FUNC and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
109-3C2 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG3k |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Functional studies (0, 02-2, 0 µg/ml without azide). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been esta |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: |
MS4A1 |
| Gene ID: |
931 |
| Uniprot ID: |
CD20_HUMAN |
| Immunogen: |
A BALB/c mouse was immunized with stimulated human leucocytes. Fusion partner: NS-1. |
| Tissue Specificity | Expressed on B-cells. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibodyAnti-B-Lymphocyte Surface Antigen B1 antibodyAnti-Bp35 antibodyAnti-Leukocyte Surface Antigen Leu-16 antibodyAnti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibodyAnti-Cd Antigen Cd20 antibodyAnti-MS4A1 antibodyAnti-CD20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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