| Short Description : | Rabbit polyclonal anti-T-cell surface glycoprotein CD1e, membrane-associated (321-370 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD1E |
| Gene ID: | 913 |
| Uniprot ID: | CD1E_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CD1E at the amino acid range 321-370 |
| Immunogen Region: | 321-370 aa |
| Specificity: | CD1E Polyclonal Antibody detects endogenous levels of CD1E protein. |
| Post Translational Modifications | Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form. |
| Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
| Protein Name | T-Cell Surface Glycoprotein Cd1e - Membrane-AssociatedHcd1eR2g1Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - SolubleScd1e |
| Database Links | |
| Cellular Localisation | T-Cell Surface Glycoprotein Cd1eMembrane-Associated: Golgi Apparatus MembraneSingle-Pass Type I Membrane ProteinEarly EndosomeLate EndosomePredominantly Localized In The Trans-Golgi Network In Immature Dendritic CellsAnd As A CleavedSoluble Protein In The Lysosome Lumen Of Mature Dendritic CellsSoluble: Lysosome Lumen |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1e - Membrane-Associated antibodyAnti-Hcd1e antibodyAnti-R2g1 antibodyAnti-Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble antibodyAnti-Scd1e antibodyAnti-CD1E antibody |
Information sourced from Uniprot.org
