![Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200790/412972/STJN000177-SDS-PAGE-1__41640.1749232498.jpg?c=1 "Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)")
![Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200790/412972/STJN000177-SDS-PAGE-1__41640.1749232498.jpg?c=1 "Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)")
Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-C-X-C Chemokine Receptor Type 2 is suitable for use in ELISA, Immunofluorescence, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IF/IP/WB |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1360 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CXCR2 |
| Gene ID | 3579 |
| Uniprot ID | CXCR2_HUMAN |
Additional Info
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Cdw128bGro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BIl-8 Receptor Type 2Cd Antigen Cd182 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Nanobody Names | Anti-C-X-C Chemokine Receptor Type 2 nanobodyAnti-Cxc-R2 nanobodyAnti-Cxcr-2 nanobodyAnti-Cdw128b nanobodyAnti-Gro/Mgsa Receptor nanobodyAnti-High Affinity Interleukin-8 Receptor B nanobodyAnti-Il-8r B nanobodyAnti-Il-8 Receptor Type 2 nanobodyAnti-Cd Antigen Cd182 nanobodyAnti-CXCR2 nanobodyAnti-IL8RB nanobody |
Information sourced from Uniprot.org