| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CD180 antigen (221-270 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD180 |
| Gene ID: | 4064 |
| Uniprot ID: | CD180_HUMAN |
| Immunogen Region: | 221-270 aa |
| Specificity: | CD180 Polyclonal Antibody detects endogenous levels of CD180 protein. |
| Immunogen: | Synthesized peptide derived from CD180 antigen at the amino acid range 221-270 |
| Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. |
| Protein Name | Cd180 AntigenLymphocyte Antigen 64Radioprotective 105 Kda ProteinCd Antigen Cd180 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd180 Antigen antibodyAnti-Lymphocyte Antigen 64 antibodyAnti-Radioprotective 105 Kda Protein antibodyAnti-Cd Antigen Cd180 antibodyAnti-CD180 antibodyAnti-LY64 antibodyAnti-RP105 antibody |
Information sourced from Uniprot.org