Anti-CD18 antibody [CLB-LFA-1/1] {FITC} (STJ16101399)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationFITC
ImmunogenHuman CD18
General Information
| Short Description | Mouse monoclonal anti-CD18 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | CLB-LFA-1/1 |
| Conjugation | FITC |
| Formulation | PBS with BSA and 0.1% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Human CD18 |
Additional Info
| Background | CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1) , alphaMbeta2 (CD11b/CD18, Mac-1, CR3) , alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts. |
Information sourced from Uniprot.org