| Short Description : | Rabbit monoclonal CD172b antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Isotype: | IgG |
| Conjugation: | ABflo® 647 |
| Purification: | Affinity purification |
| Dilution Range: | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation: | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction: | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
| Gene Symbol: | SIRPB1 |
| Gene ID: | 10326 |
| Uniprot ID: | SIRB1_HUMAN |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Tissue Specificity | Detected in monocytes and dendritic cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. |
| Protein Name | Signal-Regulatory Protein Beta-1Sirp-Beta-1Cd172 Antigen-Like Family Member BCd Antigen Cd172b |
| Database Links | Reactome: R-HSA-2172127Reactome: R-HSA-391160Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Signal-Regulatory Protein Beta-1 antibodyAnti-Sirp-Beta-1 antibodyAnti-Cd172 Antigen-Like Family Member B antibodyAnti-Cd Antigen Cd172b antibodyAnti-SIRPB1 antibody |
Information sourced from Uniprot.org