Anti-CD172a/SIRP Alpha antibody [P84] {EF488} (STJA0016498)

SKU:
STJA0016498
€184.38 - €340.63
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Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : Rat monoclonal antibody anti-CD172a/SIRP Alpha is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : P84
Conjugation: EF488
Isotype: IgG1k
Formulation: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Purification: Affinity purified
Storage Instruction: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Gene Symbol: Cd34
Gene ID: 12490
Uniprot ID: CD34_MOUSE
Tissue Specificity Expressed in the kidney where it is detected in the thin limb of Henle's loop (at protein level). Highly expressed in hematopoietic progenitor cell lines, brain and testis, and moderately in the thymus, spleen, and bone marrow, but not in adult liver.
Post Translational Modifications Highly glycosylated. Phosphorylated on serine residues by PKC.
Function Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Protein Name Hematopoietic Progenitor Cell Antigen Cd34
Cd Antigen Cd34
Database Links Reactome: R-MMU-198933
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibody
Anti-Cd Antigen Cd34 antibody
Anti-Cd34 antibody

Information sourced from Uniprot.org