Anti-CD172a/b antibody [SE5A5] {EF700} (STJA0042328)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationEF700
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal anti-CD172a/b for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SE5A5 |
| Isotype | IgG1k |
| Conjugation | EF700 |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | SIRPB1 |
| Gene ID | 10326 |
| Uniprot ID | SIRB1_HUMAN |
Additional Info
| Tissue Specificity | Detected in monocytes and dendritic cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. |
| Protein Name | Signal-Regulatory Protein Beta-1Sirp-Beta-1Cd172 Antigen-Like Family Member BCd Antigen Cd172b |
| Database Links | Reactome: R-HSA-2172127Reactome: R-HSA-391160Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Signal-Regulatory Protein Beta-1 antibodyAnti-Sirp-Beta-1 antibodyAnti-Cd172 Antigen-Like Family Member B antibodyAnti-Cd Antigen Cd172b antibodyAnti-SIRPB1 antibody |
Information sourced from Uniprot.org