Anti-CD16b antibody [SRM13470] (STJ11108200)

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STJ11108200
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Host: Rabbit
Applications: WB/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM13470
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB, 1:2000-1:4000
FC, 1:500-1:1000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR3B
Gene ID: 2215
Uniprot ID: FCG3B_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Sequence: Human
Post Translational Modifications Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B
Fc-Gamma Riii-Beta
Cd16-I
Fc-Gamma Riii
Fc-Gamma Riiib
Fcriii
Fcriiib
Fcr-10
Igg Fc Receptor Iii-1
Cd Antigen Cd16b
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Secreted After Cleavage
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B antibody
Anti-Fc-Gamma Riii-Beta antibody
Anti-Cd16-I antibody
Anti-Fc-Gamma Riii antibody
Anti-Fc-Gamma Riiib antibody
Anti-Fcriii antibody
Anti-Fcriiib antibody
Anti-Fcr-10 antibody
Anti-Igg Fc Receptor Iii-1 antibody
Anti-Cd Antigen Cd16b antibody
Anti-FCGR3B antibody
Anti-CD16B antibody
Anti-FCG3 antibody
Anti-FCGR3 antibody
Anti-IGFR3 antibody

Information sourced from Uniprot.org

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