Anti-CD164 antibody (110-190 aa) (STJ92095)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from CD164 at the amino acid range 110-190
General Information
| Short Description | Rabbit polyclonal anti-Sialomucin core protein 24 (110-190 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD164 |
| Gene ID | 8763 |
| Uniprot ID | MUC24_HUMAN |
| Immunogen | Synthesized peptide derived from CD164 at the amino acid range 110-190 |
| Immunogen Region | 110-190 aa |
| Specificity | CD164 Polyclonal Antibody detects endogenous levels of CD164 protein. |
Additional Info
| Post Translational Modifications | Highly N- and O-glycosylated.contains sialic acid. The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain. |
| Function | Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. |
| Protein Name | Sialomucin Core Protein 24Muc-24EndolynMulti-Glycosylated Core Protein 24Mgc-24Mgc-24vCd Antigen Cd164 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane ProteinEndosome MembraneCell MembraneIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialomucin Core Protein 24 antibodyAnti-Muc-24 antibodyAnti-Endolyn antibodyAnti-Multi-Glycosylated Core Protein 24 antibodyAnti-Mgc-24 antibodyAnti-Mgc-24v antibodyAnti-Cd Antigen Cd164 antibodyAnti-CD164 antibody |
Information sourced from Uniprot.org