• Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
  • Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
  • Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Anti-CD16 antibody (100-150 aa) (STJ98738)

SKU:
STJ98738

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor III-A and Low affinity immunoglobulin gamma Fc region receptor III-B (100-150 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCGR3A
FCGR3B
Gene ID: 2214
2215
Uniprot ID: FCG3A_HUMAN
FCG3B_HUMAN
Immunogen Region: 100-150 aa
Specificity: The antibody detects endogenous CD16
Immunogen: Synthetic peptide from the human protein at the amino acid range 100-150
Post Translational Modifications Glycosylated. Contains high mannose- and complex-type oligosaccharides. Glycosylation at Asn-180 is mandatory for high affinity binding to the Fc and for discrimination between fucosylated and afucosylated IgG glycoforms. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-A
Cd16a Antigen
Fc-Gamma Riii-Alpha
Fc-Gamma Riii
Fc-Gamma Riiia
Fcriii
Fcriiia
Fcr-10
Igg Fc Receptor Iii-2
Cd Antigen Cd16a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-9664323
Reactome: R-HSA-9664422
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Exists Also As A Soluble Receptor
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-A antibody
Anti-Cd16a Antigen antibody
Anti-Fc-Gamma Riii-Alpha antibody
Anti-Fc-Gamma Riii antibody
Anti-Fc-Gamma Riiia antibody
Anti-Fcriii antibody
Anti-Fcriiia antibody
Anti-Fcr-10 antibody
Anti-Igg Fc Receptor Iii-2 antibody
Anti-Cd Antigen Cd16a antibody
Anti-FCGR3A antibody
Anti-CD16A antibody
Anti-FCG3 antibody
Anti-FCGR3 antibody
Anti-IGFR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance