![Anti-CD16 antibody [LNK16] (STJ16100960)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149677/346901/STJ16100960_1__63931.1681999080.jpg?c=1 "Anti-CD16 antibody [LNK16] (STJ16100960)")
![Anti-CD16 antibody [LNK16] (STJ16100960)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149677/346901/STJ16100960_1__63931.1681999080.jpg?c=1 "Anti-CD16 antibody [LNK16] (STJ16100960)")
Anti-CD16 antibody [LNK16] (STJ16100960)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenNormal human peripheral blood granulocytes
General Information
| Short Description | Mouse monoclonal anti-CD16 for use in FC in Non-Human Primates and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Non-Human Primates/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | LNK16 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Purified by protein-A affinity chromatography. |
| Formulation | Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Normal human peripheral blood granulocytes |
Additional Info
| Background | CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and-B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype. |
Information sourced from Uniprot.org