| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CD154 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | TRAP1.3.6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.1% sodium azide |
| Concentration: | 1.0 mg/mL |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Mouse myeloma cell line transfected with human CD40L (CD154) |
| Background | Mouse anti Human CD154 antibody, clone TRAP-1 recognises the human CD40 ligand, also known as CD154, TNF-related activation protein (TRAP) or T-cell antigen Gp39. CD154 is a 261 amino acid ~32 kDa single pass, type-1 transmembrane glycoprotein (UniProt: P29965). CD154 is expressed on activated T lymphocytes, predominantly CD4 +ve and also on some basophils and mast cells.Mouse anti Human CD154 antibody, clone TRAP-1 binds to CD154 at an epitope distinct from the CD40 binding site (Kroczek et al. 1994). |
Information sourced from Uniprot.org