![Anti-CD15/FUT4/LeX antibody [FR4A5] (STJ16100998)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149714/302454/STJ16100998_1__16307.1646940642.jpg?c=1 "Anti-CD15/FUT4/LeX antibody [FR4A5] (STJ16100998)")
![Anti-CD15/FUT4/LeX antibody [FR4A5] (STJ16100998)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149714/302454/STJ16100998_1__16307.1646940642.jpg?c=1 "Anti-CD15/FUT4/LeX antibody [FR4A5] (STJ16100998)")
Anti-CD15/FUT4/LeX antibody [FR4A5] (STJ16100998)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgMk
ImmunogenA BALB/c mouse was immunized with RAJI (Burkitt's lymphoma) cells. Splenocytes were fused with mouse myeloma X63Ag8/653 cells.
General Information
| Short Description | Mouse monoclonal anti-CD15/FUT4/LeX for use in FC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | FR4A5 |
| Isotype | IgMk |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT). |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Immunogen | A BALB/c mouse was immunized with RAJI (Burkitt's lymphoma) cells. Splenocytes were fused with mouse myeloma X63Ag8/653 cells. |
Additional Info
| Background | FR4A5 reacts with CD15 (220 kDa). CD15 contains the pentasaccharide lacto-n-fucopentaose III and plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance. It is also expressed on a wide variety of other tumor cells including myeloid leukemia, breast, colorectal, and lung cancer cells. Cross reactivity has been observed with Glc Alpha 1-6glc Alpha 1-4Glc, Tn, blood group H1, and maltose. |
Information sourced from Uniprot.org