Anti-CD15 antibody [MEM-158] (STJ16100105)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenHuman granulocytes
General Information
| Short Description | Mouse monoclonal anti-CD15 for use in FC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MEM-158 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Formulation | Tris buffered saline (TBS) solution with 15 mM sodium azide |
| Storage Instruction | Store at 2-8Β°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Human granulocytes |
Additional Info
| Background | CD15 (Lewis x) , also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le (x) antigen exhibit strong self-aggregation, based on calcium-dependent Le (x)-Le (x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le (x) and its isomer sialyl-Le (a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of HodgkinΒ΄s disease. |
Information sourced from Uniprot.org