Anti-CD138 antibody [DM45] (STJA0038187)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human CD138 protein
General Information
| Short Description | Rabbit monoclonal anti-CD138 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | DM45 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | FC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SDC1 |
| Gene ID | 6382 |
| Uniprot ID | SDC1_HUMAN |
| Immunogen | Recombinant human CD138 protein |
Additional Info
| Tissue Specificity | Detected in placenta (at protein level). Detected in fibroblasts (at protein level). |
| Post Translational Modifications | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway. |
| Protein Name | Syndecan-1Synd1Cd Antigen Cd138 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022928Reactome: R-HSA-2024096Reactome: R-HSA-202733Reactome: R-HSA-3000170Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3656237Reactome: R-HSA-3656253Reactome: R-HSA-4420332Reactome: R-HSA-449836Reactome: R-HSA-9694614Reactome: R-HSA-975634Reactome: R-HSA-9820960Reactome: R-HSA-9833110 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedExtracellular ExosomeShedding Of The Ectodomain Produces A Soluble Form |
| Alternative Antibody Names | Anti-Syndecan-1 antibodyAnti-Synd1 antibodyAnti-Cd Antigen Cd138 antibodyAnti-SDC1 antibodyAnti-SDC antibody |
Information sourced from Uniprot.org