Anti-CD138 antibody [B-A38] (STJ16100321)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
STJ16100321
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General Information

Short DescriptionMouse monoclonal anti-CD138 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDB-A38
IsotypeIgG1
ConjugationUnconjugated
Dilution RangeIHC 1:25-1:200
FormulationTris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

Additional Info

Background CD138, Syndecan 1, is expressed in the late stages of B-cell differentiation with progression towards plasma cells. It can be used to differentiate lymphoplasmacytic lymphoma from marginal zone lymphoma. ALK+ large B-cell lyphoma (LBCL) usually strongly expresses CD138 whereas lineageassociated markers such as anti-CD20 and anti-CD79a do not stain ALK+LBCL. Anti-CD138 is immunoreactive with HHV8-associated primary effusion lymphoma even though the lymphoma cells lack the expression of B-cell markers. Anti-CD138 is a good marker to identify and enumerate plasma cells, benign, reactive, or malignant, in bone marrow biopsy specimens.4, 6 CD138 is also expressed in epithelial cells.

Information sourced from Uniprot.org

Citations

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