Anti-CD13 antibody [38C12] (STJ16101697)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain.
STJ16101697-1
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General Information

Short DescriptionMouse monoclonal anti-CD13 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID38C12
IsotypeIgG1
ConjugationUnconjugated
Concentration>=19 mg/L
Dilution RangeIHC-P 1:80
FormulationTissue culture supernatant with sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenRecombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain.

Additional Info

Background CD13 antigen, also known as aminopeptidase N, is a member of type II integral membrane metalloproteases, which also includes the leukocyte antigens CD10, CD26, CD73 and BP-1. CD13 antigen is a receptor for the coronaviruses which cause respiratory disease in humans and several animal species. The antigen functions as a zinc-binding metalloprotease which plays a role in cell surface antigen presentation by trimming the N-terminal amino acids from MHC class II-bound peptides. CD13 antigen is reported to be expressed on granulocytes, monocytes and their precursors, most acute myeloid leukemias and a smaller proportion of acute lymphoid leukemias. Non-hematopoietic cells which express CD13 antigen include epithelial cells, renal proximal tubules, intestinal brush border, endothelial cells, fibroblasts, brain cells, bone marrow, osteoclasts and cells lining the bile canaliculi.

Information sourced from Uniprot.org

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