• STJ73435 (1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CD13/ANPEP antibody (79-91) (STJ73435)

SKU:
STJ73435-100

£303.50
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Host: Goat
Applications: Pep-ELSA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CD13/ANPEP (79-91) is suitable for use in Pep-ELSA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ANPEP
Gene ID: 290
Uniprot ID: AMPN_HUMAN
Immunogen Region: 79-91
Accession Number: NP_001141.2
Immunogen Sequence: TLKPDSYRVTLRP
Post Translational Modifications Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form.
Function Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. (Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. (Microbial infection) Mediates as well Human cytomegalovirus (HCMV) infection.
Protein Name Aminopeptidase N
Ap-N
Hapn
Alanyl Aminopeptidase
Aminopeptidase M
Ap-M
Microsomal Aminopeptidase
Myeloid Plasma Membrane Glycoprotein Cd13
Gp150
Cd Antigen Cd13
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Also Found As A Soluble Form
Alternative Antibody Names Anti-Aminopeptidase N antibody
Anti-Ap-N antibody
Anti-Hapn antibody
Anti-Alanyl Aminopeptidase antibody
Anti-Aminopeptidase M antibody
Anti-Ap-M antibody
Anti-Microsomal Aminopeptidase antibody
Anti-Myeloid Plasma Membrane Glycoprotein Cd13 antibody
Anti-Gp150 antibody
Anti-Cd Antigen Cd13 antibody
Anti-ANPEP antibody
Anti-APN antibody
Anti-CD13 antibody
Anti-PEPN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance