Anti-CD127/IL-7R Alpha antibody {ABflo® 700} (STJ11108975)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 700
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD127/IL-7R Alpha antibody for use in FC in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 700 |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | Il7r |
| Gene ID | 16197 |
| Uniprot ID | IL7RA_MOUSE |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Spleen, thymus and fetal liver. |
| Post Translational Modifications | N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. Ubiquitinated by MARCHF8.leading to lysosomal degradation. |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Protein Name | Interleukin-7 Receptor Subunit AlphaIl-7 Receptor Subunit AlphaIl-7r Subunit AlphaIl-7r-AlphaIl-7raCd Antigen Cd127 |
| Database Links | Reactome: R-MMU-1266695Reactome: -MMU-8856825Reactome: -MMU-8856828 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-7 Receptor Subunit Alpha antibodyAnti-Il-7 Receptor Subunit Alpha antibodyAnti-Il-7r Subunit Alpha antibodyAnti-Il-7r-Alpha antibodyAnti-Il-7ra antibodyAnti-Cd Antigen Cd127 antibodyAnti-Il7r antibody |
Information sourced from Uniprot.org