Anti-CD125/IL5RA antibody [SAA0047] (STJA0027066)

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STJA0027066-100
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Short Description :Mouse monoclonal Interleukin-5 Receptor Subunit Alpha antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0047
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:1 mg/ml
Purification:Protein A/G purified from cell culture supernatant.
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:IL5RA
Gene ID:3568
Uniprot ID:IL5RA_HUMAN
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Interleukin-5 Receptor Subunit Alpha
Il-5 Receptor Subunit Alpha
Il-5r Subunit Alpha
Il-5r-Alpha
Il-5ra
Cdw125
Cd Antigen Cd125
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-5 Receptor Subunit Alpha antibody
Anti-Il-5 Receptor Subunit Alpha antibody
Anti-Il-5r Subunit Alpha antibody
Anti-Il-5r-Alpha antibody
Anti-Il-5ra antibody
Anti-Cdw125 antibody
Anti-Cd Antigen Cd125 antibody
Anti-IL5RA antibody
Anti-IL5R antibody

Information sourced from Uniprot.org