![C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000078) [Used at 0.2 ยตg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/144931/291600/STJA0000078_1__04819.1631205380.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000078) [Used at 0.2 ยตg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control")
![C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000078) [Used at 0.2 ยตg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/144931/291600/STJA0000078_1__04819.1631205380.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD11c antibody (STJA0000078) [Used at 0.2 ยตg/10<sup>6</sup> cells dilution] and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC Conjugated) (Right) were used as control")
Anti-CD11c/Itgax antibody [N418] {AF488} (STJA0000078)
SPECIFICATIONS
ClonalityMonoclonal
HostArmenian Hamster
ConjugationAF488
IsotypeIgG
General Information
| Short Description | Armenian Hamster monoclonal anti-Integrin alpha-X for use in FC in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N418 |
| Isotype | IgG |
| Conjugation | AF488 |
| Concentration | 0.5 mg/mL |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8ยฐC and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | Itgax |
| Gene ID | 16411 |
| Uniprot ID | ITAX_MOUSE |
Additional Info
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Protein Name | Integrin Alpha-XCd11 Antigen-Like Family Member CLeukocyte Adhesion Glycoprotein P150 -95 Alpha ChainLeukocyte Adhesion Receptor P150 -95Cd Antigen Cd11c |
| Database Links | Reactome: R-MMU-202733Reactome: -MMU-216083Reactome: -MMU-3000178Reactome: -MMU-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-X antibodyAnti-Cd11 Antigen-Like Family Member C antibodyAnti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibodyAnti-Leukocyte Adhesion Receptor P150 -95 antibodyAnti-Cd Antigen Cd11c antibodyAnti-Itgax antibody |
Information sourced from Uniprot.org