| Host: | Mouse |
| Applications: | IF/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD11c is suitable for use in Immunofluorescence and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | FK24 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
| Dilution Range: | IF 1:5IHC 1:5 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Gene Symbol: | ITGAX |
| Gene ID: | 3687 |
| Uniprot ID: | ITAX_HUMAN |
| Immunogen: | AML-blasts |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Protein Name | Integrin Alpha-XCd11 Antigen-Like Family Member CLeu M5Leukocyte Adhesion Glycoprotein P150 -95 Alpha ChainLeukocyte Adhesion Receptor P150 -95Cd Antigen Cd11c |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-X antibodyAnti-Cd11 Antigen-Like Family Member C antibodyAnti-Leu M5 antibodyAnti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibodyAnti-Leukocyte Adhesion Receptor P150 -95 antibodyAnti-Cd Antigen Cd11c antibodyAnti-ITGAX antibodyAnti-CD11C antibody |
Information sourced from Uniprot.org
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