Anti-CD11a antibody [38] (STJ16101904)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal anti-CD11a for use in IHC-F, FC, IF and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/FC/IF/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 38 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Formulation | PBS with <0.1% sodium azide |
| Storage Instruction | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Target Information
| Gene Symbol | CDK11A |
| Gene ID | 728642 |
| Uniprot ID | CD11A_HUMAN |
Additional Info
| Tissue Specificity | Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. |
| Post Translational Modifications | During apoptosis, induced by Fas or tumor necrosis factor, specific CKD11 p110 isoforms are cleaved by caspases to produce a protein (p110C) that contains the C-terminal kinase domain of the CDK11 proteins. |
| Function | Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. |
| Protein Name | Cyclin-Dependent Kinase 11aCell Division Cycle 2-Like Protein Kinase 2Cell Division Protein Kinase 11aGalactosyltransferase-Associated Protein Kinase P58/GtaPitslre Serine/Threonine-Protein Kinase Cdc2l2 |
| Database Links | Reactome: R-HSA-380270 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 11a antibodyAnti-Cell Division Cycle 2-Like Protein Kinase 2 antibodyAnti-Cell Division Protein Kinase 11a antibodyAnti-Galactosyltransferase-Associated Protein Kinase P58/Gta antibodyAnti-Pitslre Serine/Threonine-Protein Kinase Cdc2l2 antibodyAnti-CDK11A antibodyAnti-CDC2L2 antibodyAnti-CDC2L3 antibodyAnti-PITSLREB antibody |
Information sourced from Uniprot.org