Anti-CD117 antibody [EP10] (STJ16101809)

SKU:
STJ16101809-1

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-CD117 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EP10
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=13 mg/L
Dilution Range: IHC-P 1:200
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: A synthetic peptide corresponding to residues in the C-terminus of human CD117 protein.
Background The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117) , which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST) , small lung cell carcinomas and in melanomas.

Information sourced from Uniprot.org

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