Anti-CD114 antibody [DM172] (STJA0038157)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human CD114 protein
General Information
| Short Description | Rabbit monoclonal anti-CD114 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | DM172 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | FC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CSF3R |
| Gene ID | 1441 |
| Uniprot ID | CSF3R_HUMAN |
| Immunogen | Recombinant human CD114 protein |
Additional Info
| Tissue Specificity | One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta. |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
| Protein Name | Granulocyte Colony-Stimulating Factor ReceptorG-Csf ReceptorG-Csf-RCd Antigen Cd114 |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9616222Reactome: R-HSA-9674555Reactome: R-HSA-9705462 |
| Cellular Localisation | Isoform 2: SecretedCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Granulocyte Colony-Stimulating Factor Receptor antibodyAnti-G-Csf Receptor antibodyAnti-G-Csf-R antibodyAnti-Cd Antigen Cd114 antibodyAnti-CSF3R antibodyAnti-GCSFR antibody |
Information sourced from Uniprot.org