Anti-CD112R/PVRIG antibody [CPA.7.021] (STJA0026938)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Transmembrane Protein Pvrig antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | CPA.7.021 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PVRIG |
| Gene ID | 79037 |
| Uniprot ID | PVRIG_HUMAN |
Additional Info
| Function | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. |
| Protein Name | Transmembrane Protein PvrigCd112 ReceptorCd112rPoliovirus Receptor-Related Immunoglobulin Domain-Containing Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protein Pvrig antibodyAnti-Cd112 Receptor antibodyAnti-Cd112r antibodyAnti-Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein antibodyAnti-PVRIG antibodyAnti-C7orf15 antibody |
Information sourced from Uniprot.org