Anti-CD103/Itgae antibody [M290] (STJA0001551)
SPECIFICATIONS
ClonalityMonoclonal
HostRat
ConjugationUnconjugated
IsotypeIgG2ak
General Information
| Short Description | Rat monoclonal anti-Integrin alpha-E for use in FC, IHC and IP in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC/IP |
| Host | Rat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M290 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Formulation | PBS with 0.05% Proclin300 |
| Storage Instruction | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Target Information
| Gene Symbol | Itgae |
| Gene ID | 16407 |
| Uniprot ID | ITAE_MOUSE |
Additional Info
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall. |
| Protein Name | Integrin Alpha-EIntegrin Alpha M290Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain |
| Database Links | Reactome: R-MMU-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-E antibodyAnti-Integrin Alpha M290 antibodyAnti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibodyAnti-Itgae antibody |
Information sourced from Uniprot.org