Anti-CD103 antibody (775-855) [ZR404] (STJ180603)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human ITGAE/CD103 protein fragment (aa 775-855)
General Information
| Short Description | Rabbit monoclonal CD103 (775-855) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR404 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | ITGAE |
| Gene ID | 3682 |
| Uniprot ID | ITAE_HUMAN |
| Immunogen | Recombinant human ITGAE/CD103 protein fragment (aa 775-855) |
| Immunogen Region | 775-855 |
| Specificity | Positive Control: colon |
Additional Info
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Protein Name | Integrin Alpha-EHml-1 AntigenIntegrin Alpha-IelMucosal Lymphocyte 1 AntigenCd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain |
| Database Links | Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-E antibodyAnti-Hml-1 Antigen antibodyAnti-Integrin Alpha-Iel antibodyAnti-Mucosal Lymphocyte 1 Antigen antibodyAnti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibodyAnti-ITGAE antibody |
Information sourced from Uniprot.org