Anti-CD101 antibody [BB27] {FITC} (STJ16100561)

SKU:
STJ16100561

Current Stock:
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Mouse monoclonal antibody anti-CD101 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: BB27
Conjugation: FITC
Isotype: IgG1
Formulation: PBS with 0.09% sodium azide and 1% BSA
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: CD101
Gene ID: 9398
Uniprot ID: IGSF2_HUMAN
Tissue Specificity Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.
Post Translational Modifications N-glycosylated.
Function Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Protein Name Immunoglobulin Superfamily Member 2
Igsf2
Cell Surface Glycoprotein V7
Glu-Trp-Ile Ewi Motif-Containing Protein 101
Ewi-101
Cd Antigen Cd101
Database Links Reactome: R-HSA-202433
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Immunoglobulin Superfamily Member 2 antibody
Anti-Igsf2 antibody
Anti-Cell Surface Glycoprotein V7 antibody
Anti-Glu-Trp-Ile Ewi Motif-Containing Protein 101 antibody
Anti-Ewi-101 antibody
Anti-Cd Antigen Cd101 antibody
Anti-CD101 antibody
Anti-EWI101 antibody
Anti-IGSF2 antibody
Anti-V7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance