Anti-CD100/SEMA4D antibody [SAA0332] (STJA0027533)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Semaphorin-4d antibody for use in FC, FuncS and Neut in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/FuncS/Neut |
| Host | Mouse |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0332 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1.84 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | Sema4d |
| Gene ID | 20354 |
| Uniprot ID | SEM4D_MOUSE |
Additional Info
| Function | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system.induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
| Protein Name | Semaphorin-4dM-Sema GSemaphorin-C-Like 2Semaphorin-JSema JCd Antigen Cd100 |
| Database Links | Reactome: R-MMU-416550Reactome: -MMU-416572Reactome: -MMU-416700 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Semaphorin-4d antibodyAnti-M-Sema G antibodyAnti-Semaphorin-C-Like 2 antibodyAnti-Semaphorin-J antibodyAnti-Sema J antibodyAnti-Cd Antigen Cd100 antibodyAnti-Sema4d antibodyAnti-Semacl2 antibodyAnti-Semaj antibody |
Information sourced from Uniprot.org