Anti-CD100/SEMA4D antibody [SAA0331] {APC} (STJA0029645)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationAPC
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Semaphorin-4d antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0331 |
| Isotype | IgG1k |
| Conjugation | APC |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | SEMA4D |
| Gene ID | 10507 |
| Uniprot ID | SEM4D_HUMAN |
Additional Info
| Function | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system.induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
| Protein Name | Semaphorin-4dA8Bb18Gr3Cd Antigen Cd100 |
| Database Links | Reactome: R-HSA-416550Reactome: R-HSA-416572Reactome: R-HSA-416700 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Semaphorin-4d antibodyAnti-A8 antibodyAnti-Bb18 antibodyAnti-Gr3 antibodyAnti-Cd Antigen Cd100 antibodyAnti-SEMA4D antibodyAnti-C9orf164 antibodyAnti-CD100 antibodyAnti-SEMAJ antibody |
Information sourced from Uniprot.org