Anti-CD100 antibody [133.1G6] (STJ16100144)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenPHA stimulated PBL
General Information
| Short Description | Mouse monoclonal anti-CD100 for use in FC and IHC-F in Human, Cow and Baboon samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC-F |
| Host | Mouse |
| Reactivity | Human/Cow/Baboon |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 133.1G6 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Concentration | 100 Mu g/mL |
| Formulation | PBS with 0.02% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | SEMA4D |
| Gene ID | 10507 |
| Uniprot ID | SEM4D_HUMAN |
| Immunogen | PHA stimulated PBL |
Additional Info
| Tissue Specificity | Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. |
| Function | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system.induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
| Protein Name | Semaphorin-4dA8Bb18Gr3Cd Antigen Cd100 |
| Database Links | Reactome: R-HSA-416550Reactome: R-HSA-416572Reactome: R-HSA-416700 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Semaphorin-4d antibodyAnti-A8 antibodyAnti-Bb18 antibodyAnti-Gr3 antibodyAnti-Cd Antigen Cd100 antibodyAnti-SEMA4D antibodyAnti-C9orf164 antibodyAnti-CD100 antibodyAnti-SEMAJ antibody |
Information sourced from Uniprot.org