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![Anti-CD10 antibody [B-E3] {FITC} (STJA0018269)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/186985/412545/STJA0018269_1__34935.1747839596.png?c=1 "Anti-CD10 antibody [B-E3] {FITC} (STJA0018269)")
Anti-CD10 antibody [B-E3] {FITC} (STJA0018269)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationFITC
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal anti-Neprilysin for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR RESEARCH USE ONLY (RUO). |
Product Properties
| Clonality | Monoclonal |
| Clone ID | B-E3 |
| Isotype | IgG2a |
| Conjugation | FITC |
| Purification | Protein A purification |
| Dilution Range | Please carry out application specific titration to determine the most appropriate dilution ratio. |
| Formulation | PBS with 0.2% BSA, and 0.09% Sodium Azide |
| Storage Instruction | Shipped on gel ice packs. Store at 2-8C on arrival. |
Target Information
| Gene Symbol | MME |
| Gene ID | 4311 |
| Uniprot ID | NEP_HUMAN |
Additional Info
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Protein Name | NeprilysinAtriopeptidaseCommon Acute Lymphocytic Leukemia AntigenCallaEnkephalinaseNeutral Endopeptidase 24.11NepNeutral EndopeptidaseSkin Fibroblast ElastaseSfeCd Antigen Cd10 |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-5578768Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Neprilysin antibodyAnti-Atriopeptidase antibodyAnti-Common Acute Lymphocytic Leukemia Antigen antibodyAnti-Calla antibodyAnti-Enkephalinase antibodyAnti-Neutral Endopeptidase 24.11 antibodyAnti-Nep antibodyAnti-Neutral Endopeptidase antibodyAnti-Skin Fibroblast Elastase antibodyAnti-Sfe antibodyAnti-Cd Antigen Cd10 antibodyAnti-MME antibodyAnti-EPN antibody |
Information sourced from Uniprot.org