Anti-CCT5 nanobody [SAA1374] (STJN000230)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-T-Complex Protein 1 Subunit Epsilon is suitable for use in BImmunofluorescence, ELISA and Immunoprecipitation research applications. |
| Applications | BIF/ELISA/IP |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1374 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CCT5 |
| Gene ID | 22948 |
| Uniprot ID | TCPE_HUMAN |
Additional Info
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit EpsilonTcp-1-EpsilonCct-EpsilonChaperonin Containing T-Complex Polypeptide 1 Subunit 5 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Nanobody Names | Anti-T-Complex Protein 1 Subunit Epsilon nanobodyAnti-Tcp-1-Epsilon nanobodyAnti-Cct-Epsilon nanobodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 5 nanobodyAnti-CCT5 nanobodyAnti-CCTE nanobodyAnti-KIAA0098 nanobody |
Information sourced from Uniprot.org