Anti-CCR7 antibody (330-377) (STJ116918)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCR7 (330-377) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCR7 |
| Gene ID | 1236 |
| Uniprot ID | CCR7_HUMAN |
| Immunogen Region | 330-377 |
| Immunogen Sequence | GVKFRNDLFKLFKDLGCLSQ EQLRQWSSCRHIRRSSMSVE AET |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 330-372 of human CCR7 (NP_001829.1). |
Additional Info
| Tissue Specificity | Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. |
| Function | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
| Protein Name | C-C Chemokine Receptor Type 7C-C Ckr-7Cc-Ckr-7Ccr-7Blr2Cdw197Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1Ebi1Ebv-Induced G-Protein Coupled Receptor 1Mip-3 Beta ReceptorCd Antigen Cd197 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 7 antibodyAnti-C-C Ckr-7 antibodyAnti-Cc-Ckr-7 antibodyAnti-Ccr-7 antibodyAnti-Blr2 antibodyAnti-Cdw197 antibodyAnti-Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1 antibodyAnti-Ebi1 antibodyAnti-Ebv-Induced G-Protein Coupled Receptor 1 antibodyAnti-Mip-3 Beta Receptor antibodyAnti-Cd Antigen Cd197 antibodyAnti-CCR7 antibodyAnti-CMKBR7 antibodyAnti-EBI1 antibodyAnti-EVI1 antibody |
Information sourced from Uniprot.org