Anti-CCP4 antibody (748-761) (STJ72627)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CCP4 (748-761) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave bands at approx 100kDa and 24kDa in HeLa lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | AGBL1 |
| Gene ID | 123624 |
| Uniprot ID | CBPC4_HUMAN |
| Accession Number | NP_689549.2 |
| Immunogen Region | 748-761 |
| Immunogen Sequence | RPYQVITARVHPGE |
Additional Info
| Function | Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. |
| Protein Name | Cytosolic Carboxypeptidase 4Atp/Gtp-Binding Protein-Like 1Protein Deglutamylase Ccp4 |
| Database Links | Reactome: R-HSA-8955332 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic Carboxypeptidase 4 antibodyAnti-Atp/Gtp-Binding Protein-Like 1 antibodyAnti-Protein Deglutamylase Ccp4 antibodyAnti-AGBL1 antibodyAnti-CCP4 antibody |
Information sourced from Uniprot.org