| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CCP4 (748-761) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave bands at approx 100kDa and 24kDa in HeLa lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | AGBL1 |
| Gene ID: | 123624 |
| Uniprot ID: | CBPC4_HUMAN |
| Immunogen Region: | 748-761 |
| Accession Number: | NP_689549.2 |
| Immunogen Sequence: | RPYQVITARVHPGE |
| Function | Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. |
| Protein Name | Cytosolic Carboxypeptidase 4Atp/Gtp-Binding Protein-Like 1Protein Deglutamylase Ccp4 |
| Database Links | Reactome: R-HSA-8955332 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic Carboxypeptidase 4 antibodyAnti-Atp/Gtp-Binding Protein-Like 1 antibodyAnti-Protein Deglutamylase Ccp4 antibodyAnti-AGBL1 antibodyAnti-CCP4 antibody |
Information sourced from Uniprot.org