Anti-CCL8 antibody (50-99 aa) (STJ96658)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human CCL8 at the amino acid range 50-99
STJ96658
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General Information

Short DescriptionRabbit polyclonal anti-C-C motif chemokine 8 (50-99 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA/IHC
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCCL8
Gene ID6355
Uniprot IDCCL8_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human CCL8 at the amino acid range 50-99
Immunogen Region50-99 aa
SpecificityMCP-2 Polyclonal Antibody detects endogenous levels of MCP-2 protein.

Additional Info

Post Translational Modifications N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein Name C-C Motif Chemokine 8
Hc14
Monocyte Chemoattractant Protein 2
Monocyte Chemotactic Protein 2
Mcp-2
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76
Database Links
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 8 antibody
Anti-Hc14 antibody
Anti-Monocyte Chemoattractant Protein 2 antibody
Anti-Monocyte Chemotactic Protein 2 antibody
Anti-Mcp-2 antibody
Anti-Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 antibody
Anti-CCL8 antibody
Anti-MCP2 antibody
Anti-SCYA10 antibody
Anti-SCYA8 antibody

Information sourced from Uniprot.org

Citations

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