![Anti-CCL3/MIP-1-alpha nanobody [SAA1270] (STJN000132)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200745/412927/STJN000132-SDS-PAGE-1__08715.1749232460.jpg?c=1 "Anti-CCL3/MIP-1-alpha nanobody [SAA1270] (STJN000132)")
![Anti-CCL3/MIP-1-alpha nanobody [SAA1270] (STJN000132)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200745/412927/STJN000132-SDS-PAGE-1__08715.1749232460.jpg?c=1 "Anti-CCL3/MIP-1-alpha nanobody [SAA1270] (STJN000132)")
Anti-CCL3/MIP-1-alpha nanobody [SAA1270] (STJN000132)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-C-C Motif Chemokine 3 is suitable for use in ELISA and RIA research applications. |
| Applications | ELISA/RIA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1270 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CCL3 |
| Gene ID | 6348 |
| Uniprot ID | CCL3_HUMAN |
Additional Info
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Nanobody Names | Anti-C-C Motif Chemokine 3 nanobodyAnti-G0/G1 Switch Regulatory Protein 19-1 nanobodyAnti-Macrophage Inflammatory Protein 1-Alpha nanobodyAnti-Mip-1-Alpha nanobodyAnti-Pat 464.1 nanobodyAnti-Sis-Beta nanobodyAnti-Small-Inducible Cytokine A3 nanobodyAnti-Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 nanobodyAnti-Ld78-Alpha(4-69 nanobodyAnti-CCL3 nanobodyAnti-G0S19-1 nanobodyAnti-MIP1A nanobodyAnti-SCYA3 nanobody |
Information sourced from Uniprot.org