Anti-CCL3 antibody (26-75 aa) (STJ94130)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MIP-1alpha at the amino acid range 26-75
General Information
| Short Description | Rabbit polyclonal anti-C-C motif chemokine 3 (26-75 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL3 |
| Gene ID | 6348 |
| Uniprot ID | CCL3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MIP-1alpha at the amino acid range 26-75 |
| Immunogen Region | 26-75 aa |
| Specificity | MIP-1 Alpha Polyclonal Antibody detects endogenous levels of MIP-1 Alpha protein. |
Additional Info
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 3 antibodyAnti-G0/G1 Switch Regulatory Protein 19-1 antibodyAnti-Macrophage Inflammatory Protein 1-Alpha antibodyAnti-Mip-1-Alpha antibodyAnti-Pat 464.1 antibodyAnti-Sis-Beta antibodyAnti-Small-Inducible Cytokine A3 antibodyAnti-Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 antibodyAnti-Ld78-Alpha(4-69 antibodyAnti-CCL3 antibodyAnti-G0S19-1 antibodyAnti-MIP1A antibodyAnti-SCYA3 antibody |
Information sourced from Uniprot.org